Zeger Debyser

Research Partner

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Expertise

* Viral vector technology
* Assay development for phenotypic drug screens using high content imaging
* Drug discovery and development

Relevant Publications

Phenotyping of Rare CFTR Mutations Reveals Distinct Trafficking and Functional Defects
Marjolein Ensinck, Liesbeth De Keersmaecker, Lise Heylen, Anabela S. Ramalho, Rik Gijsbers, Ricard Farré, Kris De Boeck, Frauke Christ, Zeger Debyser, Marianne S. Carlon
Published in Cells, March 2020 (see publication in Journal or Research Gate )

Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing
Giulia Maule, Antonio Casini, Claudia Montagna, Anabela S. Ramalho, Kris De Boeck, Zeger Debyser, Marianne S. Carlon, Gianluca Petris, Anna Cereseto
Published in Nature Communications, August 2019 (see publication in Journal or Research Gate )

ArAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice
Dragana Vidović, Marianne S. Carlon, Mélanie F. da Cunha, Johanna F. Dekkers, Monika I. Hollenhorst, Marcel J. C. Bijvelds, Anabela S. Ramalho, Chris Van den Haute, Marc Ferrante, Veerle Baekelandt, Hettie M. Janssens, Kris De Boeck, Isabelle Sermet-Gaudelus, Hugo R. de Jonge, Rik Gijsbers, Jeffrey M. Beekman, Aleksander Edelman, Zeger Debyser
Published in American Journal of Respiratory and Critical Care Medicine, September 2015 (see publication in Journal or Research Gate )